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Healing
TB500 5mg
PURITY
≥99.5% HPLC
STORAGE
−20°C · Lyophilized

TB500

TISSUE RESEARCH
CAS77591-33-4MW4963.5 g/molFORMULAC212H350N56O78SCATEGORYHealing
SELECT VIAL
PRICE
$62.50/ VIAL
QUANTITY
01
FOR IN VITRO LABORATORY RESEARCH ONLY. NOT FOR HUMAN OR VETERINARY USE. NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE. NOT EVALUATED BY THE FDA. PURCHASER MUST BE 21 OR OLDER.

What is TB-500?

TB-500 (Thymosin Beta-4 Fragment) is a synthetic 43-amino acid peptide representing the active region of the naturally occurring Thymosin Beta-4 protein. With the molecular formula C₂₁₂H₃₅₀N₅₆O₇₈S and a molecular weight of 4963.5 g/mol (CAS: 77591-33-4), TB-500 is the research designation for the peptide fragment containing the primary bioactive sequence of the parent protein.

Amino Acid Sequence:Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH
Classification: Actin-Binding Peptide FragmentActin CytoskeletonG-Actin Binding

Specifications

CAS Number77591-33-4
Molecular FormulaC212H350N56O78S
Molecular Weight4963.5 g/mol
Purity≥99.5% (HPLC verified)
FormLyophilized powder
Storage−20°C · Lyophilized
ShippingInsulated protective packaging

Mechanism of Action

Actin Cytoskeleton

G-actin sequestration

TB-500 binds to monomeric G-actin, regulating actin polymerization and cytoskeletal dynamics in cell culture models.

Cell Migration

Integrin signaling

Published studies demonstrate effects on cell motility through interactions with integrin receptors and focal adhesion dynamics.

Storage & Handling

Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Store the lyophilized powder sealed at −20°C, protected from light and moisture, and minimize temperature fluctuations to preserve compound integrity during long-term storage.

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

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